This study has been carried out to compile and to find the best production route for the
production of by 81Rb comparing the cross section data of different charged particle
induced(reactions induced by p,d,3He and α) on 112Sn,118Sn,120Sn, 124Sn, 79Br, 81Br,
natKr, 80Kr,82Kr,83Kr ,93Nb,Zn, and Ga target. The radioisotope 81Rb has long been known
to be the ideal properties for treating the disease, especially cancer. The lower betaemitter, with a half-life of 4.6 hours, has excellent chemical properties that can be used as
a radio immunotherapy. We have studied total thirty two reactions for the production of
81Rb reactions. Out of which we have selected total seven reaction namely
79Br(a,2n)81Rb,81Br(a,4n)81Rb, natKr(p,x)81Rb,
natkr(d,x)81Rb,80kr(d,n)81Rb,82kr(p,2n)81Rb,
83kr(p,3n)81Rb, 93Nb(p,x)81Rb, 112Sn(p,x)81Rb reaction, on account of their suitability to
use in diagnostic and therapeutic applications. The reactions which are not suitable for
diagnostic and therapeutic application nat Rb(p,x)81Rb,because of the radio isotopic
impurities cannot be separated chemically from the final product. The given heavy
particle induced reactions name112Sn(12c,x)81Rb,1H(197Au,F)81Rband many of them like
that reaction , not suitable for the production of 81Rb because they give product of multi
channel that may be difficult to handle at the same time and also due to the higher energy
which are not reliable of their use in diagnostic and therapeutic applications. For medical
Application we use prefer those reactions which gives higher resection at low energy
cyclotron. The experimental data for all the selected reactions were taken from IAEA on
line data source EXFOR. For comparison the excitation function’s of all selected
reactions were plotted using ORIGN software, by using their experimental information
reliability of the data were checked with each other and on the basis of their Q-values and
threshold. From above given reactions two reactions 82Kr(p,2n)81Rb
and 68Zn(p,2p)67Cu are looking more reliable for the production of 81Rb. In these
reactions the energy is low and cross-section is high; so they can be continently produced
within the hospital using low energy cyclotrons. Experimental data of selected charged
particle induced reactions were critically analyzed and compared to achieve best
production route for 81Rb Finally we suggested reaction 82Kr(p,2n)81Rb as the best
reaction because of its higher cross section at low energie