Quantitative drug design :
Martin, Yvonne Connolly,
Quantitative drug design : a critical introduction / Yvonne Connolly Martin. - 2nd ed. - Boca Raton : CRC Press/Taylor & Francis, 2010 - xv, 282 p. : ill. ; 25 cm.
1. Overview of quantitative drug design
2. Noncovalent interactions in biological systems
3. Preparation of 3d structures of molecules for 3d qsar
4. Calculating physical properties of molecules
5. Biological data
6. Form of equations relating potency and physical properties
7. Statistical basis of regression and partial least-squares analysis
8. Strategy for the statistical evaluation of a data set of related molecules
9. Detailed examples of qsar calculations on erythromycin esters
10. Case studies
11. Methods to approach other structure-activity problems.
9781420070996 (hardcover : alk. paper)
Drugs--Structure-activity relationships.
QSAR (Biochemistry)
Drugs--Design.
Drug Design.
Biopharmaceutics.
Models, Theoretical.
Quantitative Structure-Activity Relationship.
615.19 / M3791
Quantitative drug design : a critical introduction / Yvonne Connolly Martin. - 2nd ed. - Boca Raton : CRC Press/Taylor & Francis, 2010 - xv, 282 p. : ill. ; 25 cm.
1. Overview of quantitative drug design
2. Noncovalent interactions in biological systems
3. Preparation of 3d structures of molecules for 3d qsar
4. Calculating physical properties of molecules
5. Biological data
6. Form of equations relating potency and physical properties
7. Statistical basis of regression and partial least-squares analysis
8. Strategy for the statistical evaluation of a data set of related molecules
9. Detailed examples of qsar calculations on erythromycin esters
10. Case studies
11. Methods to approach other structure-activity problems.
9781420070996 (hardcover : alk. paper)
Drugs--Structure-activity relationships.
QSAR (Biochemistry)
Drugs--Design.
Drug Design.
Biopharmaceutics.
Models, Theoretical.
Quantitative Structure-Activity Relationship.
615.19 / M3791
