000			01894nam a22001697a 4500
999			_c21866 _d21866
005			20221018162537.0
008			221018b ||||| |||| 00| 0 eng d
020			_ahbk
082			_a591 _bEs86
100			_aSadia Afzal, _bBS Zoology, _c2015-2019, _dSupervised by Dr. Asma Chaudhary
245			_aEstimation of minimal inhibitory concentration against ligand and metal (II) complexes _c/ Sadia Afzal
260			_aLahore : _bDivision of Science & Technology, University of Education, _c2019
300			_axi, 55 p. _eCD
520			_aThe antibacterial activity of the synthesized derivatives (collected from chemistry department) was evaluated using a broth dilution method against bacterial pathogen. The concentration of compound was 1.5mg/ml. Ciprofloxin was a reference compound to be used as positive control. The compounds exhibited percent antibiosis against Escherichia coli (48.97%-99.64%), Pseudomonas aeruginosa (34.78%-99.52%), Staphylococcus aureus (37.24%-99.63%), Klebsiella sp. (34.88%-99.34%). Bis(3-(1-(2-hydroxy phenyl imino ethyl) dihydrofuran-2(3H)-one)nickel(II) nitrate (AK-30) showed better antibiotic potential against three pathogens Escherichia coli, Staphylococcus aureus, Klebsiella sp. that has percent antibiosis ( >98%) while this compound showed resistant antibiosis against Pseudomonas aeruginosa that was (-40.09%). Bis(3-(1-(phenylimino)ethyl) dihydrofuran-2(3H)-one)copper(II) chloride(KS-33) Showed resistant/poor antibiotic potential against two pathogens Pseudomonas aeruginosa and Staphylococcus aureus while the same compound showed antibiotic results against Escherichia coli and Klebsiella sp. that was >99%. Key words: Schiff base ligand, Metallic complexes, Antimicrobial activity, Broth dilution method, Susceptibility testing, Pathogen resistance.
650			_aZoology--Estimation--Inhibitory Concentration--Metal
942			_cTH