| 000 | 03268nam a22001697a 4500 | ||
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_c21811 _d21811 |
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| 005 | 20221005175301.0 | ||
| 008 | 221005b ||||| |||| 00| 0 eng d | ||
| 020 | _ahbk | ||
| 082 |
_a530.1 _bC73822 |
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| 100 |
_aUmair Rasheed, _bMsc Physics, _c2016-2018, _dSupervised by Dr. Nouman Amjed |
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| 245 |
_aComparative study for the production possibilities of the diagnostic radionuclide Cu-67 _c/ Umair Raheed |
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| 260 |
_aLahore : _bDivision of Science & Technology, University of Education, _c2018 |
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| 300 |
_aiv, 66 p. _eCD |
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| 520 | _aThis study has been carried out to compile and to find the best production way to produce 67Cu by comparing the cross-section data of different charged particle induced reactions (induced by p, d,3He and α) on natNi, Zn, and Ga targets. The radioisotope 67Cu has long been known to be the ideal properties for treating the disease, especially cancer. The lower beta-emitter, with a half-life of 2.6 days, has excellent chemical properties that can be used as a radioimmunotherapy. We have studied total twenty reactions for the production of 67Cu; namely 64Ni(α,p)67Cu,natZn(p,x)67Cu, natZn(d,x)67Cu, 67Zn(d,2p) 67Cu, 68Zn(γ,p) 67Cu, 68Zn(p,2p)67Cu, 68Zn(p,2p)67Cu, 68Zn(d,3He)67Cu, 68Zn(α,x)67Cu, 70Zn(p, α)67Cu,70Zn(d,x) 67Cu, 69Ga(p,3p) 67Cu and 71Ga(p,x)67Cu 64Cu(α,2p)67Cu and 66Cu(n, γ)67Cu,67Zn(n,p)67Cu,68Zn(n,d) 67Cu,68Zn(n,x)67Cu, 69Ga(n,n+a) 67Cu reactions. Out of which we have selected total twelve reaction on account of their suitablity to use in diagonostic and therapeutic applications; namely 64Ni(α,p)67Cu, natZn(p,x)67Cu, natZn(d,x)67Cu, 67Zn(d,2p) 67Cu, 68Zn(γ,p) 67Cu, 68Zn(p,2p)67Cu, 68Zn(p,2p)67Cu, 68Zn(d,3He)67Cu, 68Zn(α,x)67Cu, 70Zn(p,α)67Cu,70Zn(d,x) 67Cu, 69Ga(p,3p)67Cu reactions. The 64Cu(α,2p)67Cu and 66Cu (n, γ)67Cu reactions are not suitable because the radio isotopic impurities cannot be separated chemically from the final product. The given neutron induced reactions 67Zn(n,p)67Cu,68Zn(n, d) 67Cu,68Zn(n,x)67Cu 69Ga(n,n+a) 67Cu also not suitable for the production of 67Cu because they give product at higher energy which are not reliable of their use in diagonostic and therapeutic applications. For medical Application we use prefer those reactions which gives higher cross-section at low energy cyclotron. The experimantal data for all the selected reactions were taken from IAEA on line data source EXFOR. For comparison the excitation function of all selected reactions was plotted using ORIGN software. By using their experimental information reliability of the data was checked with each other and based on their Qvalues and threshold. From above given reactions two reactions 64Ni(α, p)67Cu and 68Zn(p,2p)67Cu are looking more reliable to produce 67Cu. In these reactions the energy is low, and cross-section is high; so, they can be conveniently produced within the hospital using low energy cyclotrons. Experimental data of selected charged particle induced reactions were critically analysed and compared to achieve best production route for 67Cu Finally we suggested 64Ni (α, p)67Cu reaction as the best reaction because of its higher yield at low energies | ||
| 650 | _aPhysics--Production--Diagnostic--Radionuclide | ||
| 942 | _cTH | ||