000 01274nam a22001577a 4500
999 _c21570
_d21570
005 20220922130414.0
008 220707b ||||| |||| 00| 0 eng d
082 _a547.2
_bD4601
100 _aMaham Nisar,
_bMS(chemistry)
_c2016-2018
_dSupervised by Dr.Qamar Ali
245 _aDesign, Synthesis and Biological Activity of Chalcone Based Acetyl Pyrazoline Derivatives
_c/Maham Nisar
260 _aLahore :
_bDepartment of Chemistry, Div. S&T, University of Education,
_c2018
300 _a75
_bxv
_eCD
520 _aThis study contains synthesis, characterization and bio-screening of Acety pyrazolines. Different chalcones, pyrazolines and acetyl pyrazolines were synthesized by using acetophenone and various substituted benzaldehydes in resence of NaOH and methanol. Pyrazolines were obtained upon oxidative cyclization of synthesized chalcones in presence of hydrazine hydrate in methanol. Synthesis of acetyl pyrazolines was achieved by refluxing pyrazoline derivatives in glacial acetic acid. Structures of the compounds were confirmed by IR and EIMS. All prepared compounds were biologically screened for antioxidant and antimicrobial activity and they showed influential results.
650 _aBiological Activity - Chalcone - Acetyl Pyrazoline - Chemistry
942 _cTH