00972cam a22002294a 4500001000500000005001700005008004100022020002800063040000800091082002200099100002600121245008300147250001200230260005800242300004400300500005100344650003000395650002600425650002800451650001900479505024400498210320200708122658.0040116s2004    ne af    b    001 0 eng    a0126437327 (alk. paper)  cDLC00a615.19222bS58751 aSilverman, Richard B.14aThe organic chemistry of drug design and drug action / cRichard B. Silverman.  a2nd ed.  aAmsterdam :aBoston :bElsevier Academic Press,c2004  axix, 617 p.bill. (some col.) ;c27 cm.  aIncludes bibliographical references and index. 0aPharmaceutical chemistry. 0aBioorganic chemistry. 0aMolecular pharmacology. 0aDrugsxDesign.0 a1 . Introduction
2 . Drug discovery, design, and development
3 . Receptors
4 . Enzymes (catalytic receptors)
 5 . Enzyme inhibition and inactivation
 6 . Dna-interactive agents
 7 . Drug metabolism
 8 . Prodrugs and drug delivery systems