Human Molecular Genetics
/ Tom Strachan & Andrew Read
- 5th ed.
- Boca Raton : CRC Press Taylor & Francis Group, 2020.
- 770 p.
Contents
Preface About the Authors Contributors
Part-1:- Basic of DNA, Chromosomes, cells, development and inheritance
1. Basic Principles of Nuclei Acid Structure and Gene Expression 2. Fundamentals of Cells and Chromosomes 3. Fundamentals of Cell-Cell Interactions and Immune System Biology 4. Aspects of early Mammalian Development, Cell Differentiation, and Stem Cells 5. Patterns of Inheritance
Part - 2 :- Understanding Genomes
6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybridization, and DN Sequencing 7. Analyzing the Structure and Expression of Genes and Genomes 8. Principles of Genetic Manipulation of Mammalian Cells 9. Uncovering the Architecture and Workings of the Human Genome 10. Gene Regulation and the Epigenome
Part - 3 :- Genetic Variations between individuals and species
11. An Overview of Human Genetic Variation 12. Human Population Genetics 13. Comparative Genomics and Genome Evolution 14. Human Evolution
Part - 4 :- Human Genetics Disease
15. Chromosomal Abnormalities and Structural Variants 16. Molecular Pathology: Connecting Phenotypes to Genotypes 17. Mapping and Identifying Genes for Monogenic Disorders 18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis 19. Cancer Genetics and Genomics
Part - 5 :- Applied Human Molecular Genetics
20. Genetics Testing in Healthcare and the Law 21. Genetic Approaches to Treating Disease