Ayesha Noor Zahid, MS Physics, 2016-2018 Supervised by Dr. Nouman Amjed
Evaluation of the production of cross section of positron emitter radionuclide Ga66
/ Ayesha Noor Zahid
- Lahore : Division of Science & Technology, University of Education, 2018
- xiii,76 p. CD
66Ga is a positron emitter with half-life of T1/2=9.49 hour. It can be produced using cyclotron by charged particle induced reaction on different natural and enriched stable isotopes. 66Ga, being a positron emitter with intermediate half-life is a strong candidate for Positron emission tomography (PET). It is also used in SPECT and apart from this it can be used in theranostic pairs for theragnostic studies. With the increasing significance of 66Ga in nuclear medicine it is necessary to evaluate and validate the nuclear reaction cross section data to suggest its best possible production route. For this purpose the experimental data was collected from EXFOR and reliability of the data was checked with nuclear model calculations; such as ALICE-IPPE, TAYLS and EMPIRE. Normalization of the experimental reported data was performed according to the latest standards of decay data and monitor reactions. The production routes; 63Cu(He3,n)66Ga, 63 Cu(a,n)66Ga, 65Cu(a,3n)66Ga, natCu(a,x)66Ga, 66Zn(d,2n)66Ga, 67Zn(p,2n)66Ga, 68Zn(p,3n)66Ga, 66Zn(p,n)66Ga and natZn(p,x)66Ga were evaluated and analyzed to suggest the best possible production route for high purity production of 66Ga. Out of the evaluated nuclear reactions for the production of 66Ga; The 66Zn(p,n)66Ga reaction was found to be the best production route. So 66Zn (p,n)66Ga reaction was suggested as best; because of the possibility of its production using low energy cyclotrons. Key Words: 66Ga, PET, SPECT, Nuclear models, Data Fitting