TY  - BOOK
AU  - Arooba Rafaqat,
TI  - Ovarian Cancer and Some Epidemological Factors: A Hospital Based Study
U1  - 599 
PY  - 2018///
CY  - Lahore
PB  - Department of Zoology, Div. S&T University of Education
KW  - Ovarian Cancer  - Epidemological Factors - Zoology
N2  - Ovarian tumor is the sixth most basic cancer that occurs in females and is the main source of  death. The goal of present examination was the determination of epidemiological components  like history of breast and ovarian tumor, age, menstrual history, diabetes, diet and CA125 levels  (carbohydrate antigen 125, biomarker, of ovarian cancer). 200 patients were interviewed, after  getting consent, on a structured questionnaire. In addition, serum CA125 levels were studied  through ELISA test in 54 patients with ovarian cancer and 35 age-matched healthy controls.  CA125 provides useful information about the status of the disease in patients which are under  treatment. Our findings showed that 50% of the patients were analyzed at the age of 45 years,  while 75% patients were 53years old when diagnosed. . Early menarche and late menopause  were the major epidemiological factors emerged from our study. In the present study 15% of  patients had ovarian cancer running in their relatives and 20% of patients had breast cancer in  their families. Further, 3% patients of OC had breast cancer in their past. Diabetes was found  associated with the ovarian cancer, 39.5% of OC patients were diabetic. Many patients  underwent different treatment options like Hysterectomy (69.5%), radiography (39%) and  chemotherapy (95%). The CA125 values were significantly higher (p=0.034) in the case patients  compared with the control group. The results further showed that 52% of the patients with OC  were correctly diagnosed as having OC, while 83% of those without OC were correctly  diagnosed (with 48% of OC patients and 17% of non-OC patients incorrectly diagnosed). This  concluded that CA 125 is poor test which has moderate sensitivity and specificity. Key Words: OC, CA125, ELISA, diabetes, age, hysterectomy, radiography, chemotherapy
ER  -