Contents

Preface
About the Authors
Contributors


Part-1:- Basic of DNA, Chromosomes, cells, development and inheritance

1. Basic Principles of Nuclei Acid Structure and Gene Expression
2. Fundamentals of Cells and Chromosomes
3. Fundamentals of Cell-Cell Interactions and Immune System Biology
4. Aspects of early Mammalian Development, Cell Differentiation, and Stem Cells
5. Patterns of Inheritance

Part - 2 :- Understanding Genomes

6. Core DNA Technologies: Amplifying DNA, Nucleic Acid Hybridization, and DN Sequencing
7. Analyzing the Structure and Expression of Genes and Genomes
8. Principles of Genetic Manipulation of Mammalian Cells
9. Uncovering the Architecture and Workings of the Human Genome
10. Gene Regulation and the Epigenome

Part - 3 :- Genetic Variations between individuals and species

11. An Overview of Human Genetic Variation
12. Human Population Genetics
13. Comparative Genomics and Genome Evolution
14. Human Evolution

Part - 4 :- Human Genetics Disease

15. Chromosomal Abnormalities and Structural Variants
16. Molecular Pathology: Connecting Phenotypes to Genotypes
17. Mapping and Identifying Genes for Monogenic Disorders
18. Complex Disease: Identifying Susceptibility Factors and Understanding Pathogenesis
19. Cancer Genetics and Genomics

Part - 5 :- Applied Human Molecular Genetics

20. Genetics Testing in Healthcare and the Law
21. Genetic Approaches to Treating Disease

Glossary
Index