Azines are important against a range of microorganisms because they play an extensive role in living organisms. Azines has been receiving significant role as one of the alternatives for antimicrobial agents. Ten azines have been synthesized by the condensation of hydrazine hydrate and various benzaldehyde derivatives like 2-hydroxybenzaldehyde and 3,4-dimethoxybenzaldehyde .The electronic transitions within these azine molecules have been investigated by UV-Vis. spectroscopy. The 1H NMR, GC-MS and IR spectra were studied and assigned to related groups. Furthermore various metal complexes with mentioned azines have been synthesized by the reaction of titled ligands and transition metal ion [Ni (II), Cu (II)] etc.].The antimicrobial activities were evaluated against bacterial species. This novel synthesis has many advantages like economical, environmental, mild reaction conditions and simple work up with high product yield.