MARC details
| 000 -LEADER |
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| fixed length control field |
02091nam a22001697a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20221018165746.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
221018b ||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
hbk |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
591 |
| Item number |
Ev132 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| Student name |
Iram Mukhtar, |
| Class |
BS Zoology, |
| Session |
2015-2019, |
| Supervisor |
Supervised by Dr. Asma Chaudhary |
| 245 ## - TITLE STATEMENT |
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| Title |
Evaluation of bacterial growth inhibition against divalent metallic compounds of schiff base |
| Statement of responsibility, etc |
/ Iram Mukhtar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Lahore : |
| Name of publisher, distributor, etc |
Division of Science & Technology, University of Education, |
| Date of publication, distribution, etc |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
x, 60 p. |
| Accompanying material |
CD |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
The Schiff base ligand, and its metal complexes were designed and collected from<br/>Chemistry department as potential antimicrobial agents, and bioactivity could be<br/>determined following in vitro assays against human pathogens. The broth dilution method<br/>was used to determine percent antibiosis. Ten testing compounds were diluted up to<br/>1.5mg/ml. Ciprofloxacin was used as positive control. The compounds exhibited<br/>moderate to good percent antibiosis against Escherichia coli (44.48-99.73), Pseudomonas<br/>aeruginosa (31.4-99.28), Staphylococcus aureus (27.12-99.68) and Klebsiella sp. (39.53-<br/>99.84). Bis((N1Z,N2Z)-N1,N2-dibenzylideneethane-1,2-diamine)plumbum(II)acetate<br/>(MS-84) showed better antibiotic potential against four pathogens (Escherichia coli,<br/>Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella sp. with the percent<br/>antibiosis ranging from 81.22-99.39. Controversially, 3,3'-((1Z,1'Z)-(ethane-1,2-<br/>diylbis(azanylylidene))-bis(methanylylidene))diphenolcopper(II) (MS-80) inhibited two<br/>pathogens (Pseudomonas aeruginosa, Klebsiella sp. with less than 20% antibiosis while<br/>showed better antibiotic activity (>90) against other two pathogens (Staphylococcus<br/>aureus, Escherichia coli. Two designed Schiff bases i-e MS-84 and MS-80 will be<br/>promising therapeutant to be used in pharmaceutical industry.<br/>Key words:- Divalent metal complexes, Schiff base ligands, antibacterial activity, Broth<br/>dilution method, Human pathogens, antibiosis. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Zoology--Evaluation--Bacterial Growth--Metallic Compounds |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Theses |
