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Ameliorative Potential of Garlic (Allium Sativum) Against Cadmium Chloride in Developing Chick (Record no. 21699)

MARC details
000 -LEADER
fixed length control field 02663nam a22001577a 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20221021143313.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220803b ||||| |||| 00| 0 eng d
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 591.8
Item number Am32
100 ## - MAIN ENTRY--PERSONAL NAME
Student name Shabana Shoukat,
Class MPhil(Zoology)
Session 2016-2018
Supervisor Supervised by Dr.Shagufta Andleeb
245 ## - TITLE STATEMENT
Title Ameliorative Potential of Garlic (Allium Sativum) Against Cadmium Chloride in Developing Chick
Statement of responsibility, etc /Shabana Shoukat
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Lahore :
Name of publisher, distributor, etc Department of Zoology, Div. S&T University of Education,
Date of publication, distribution, etc 2018
300 ## - PHYSICAL DESCRIPTION
Extent 114 p.
Other physical details xxi
Accompanying material CD
520 ## - SUMMARY, ETC.
Summary, etc Cadmium (Cd) a toxic heavy metal is a modern pollutant associated with several industrial processes. Cadmium is absorbed in significant quantities from cigarette smoke, fossil fuel combustion, phosphate fertilizers, iron, steel, cement production, and municipal solid waste incineration and is known potential carcinogenic, mutagenic and teratogenic through bioaccumulation in tissues by ingestion and inhalation, targeting brain, liver, heart, kidneys, lungs, bones and vascular systems. Aims of present study are to analyze various developmental abnormalities by sub-lethal dose of Cadmium chloride and protective role of Garlic (Allium sativum), to minimize the intensities of these toxicities. Chick embryo was selected as the model organism. For this purpose, fertilized eggs of Gallus domesticus were randomly divided into four different groups and incubated at ±37°C. Group I was intact control (untreated). On 7th day of incubation, eggs of Group II were injected with a sub-lethal dose of Cadmium chloride (CdCl21.5 µg /0.05 ml/egg) in albumin. In group III, eggs were treated with Cadmium chloride and fresh garlic juice (CdCl2 1.5µg/0.05ml/egg + 2µg Garlic juice/0.05ml/egg), one after the other between short intervals of 10 minutes. Group IV was injected with fresh garlic juice (2µg garlic juice/0.05 ml/egg). Experiment was continued till 21st day of incubation for natural hatching and remaining embryos were recovered at 23rd day of incubation. Two days old chicks were decapitated; organs and embryos were fixed in Bouin’s fluid, and further processed for morphological, morphometric and histological analysis. Cadmium chloride induced significant developmental abnormalities such as reduced body weight, exencephaly, crooked toes, crossed beak, limbus, kyphosis, gastroschisis and severe histopathological anomalies in liver and heart tissues. Garlic has minimized these toxicities due to its potential antioxidant property. Keywords: Cadmium chloride, Allium sativum, embryotoxicity, chick embryo, antidote, fresh garlic juice.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Garlic - Cadmium Chloride - Chick – Zoology
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Theses
Holdings
Withdrawn status Damaged status Home library Current library Date acquired Full call number Barcode Date last seen Price effective from Koha item type
    UE-Central Library UE-Central Library 03.08.2022 591.8 Am32 TTH81 03.08.2022 03.08.2022 Theses
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