Synthesis, Characterization and Bioscreening of Isoxazolic Aurone Analogues (Record no. 21582)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01409nam a22001577a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220923085007.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220707b ||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 547.2 |
| Item number | Sy78 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Student name | Ayesha Kanwal, |
| Class | MPhil(chemistry) |
| Session | 2015-2017 |
| Supervisor | Supervised by Dr.Qamar Ali |
| 245 ## - TITLE STATEMENT | |
| Title | Synthesis, Characterization and Bioscreening of Isoxazolic Aurone Analogues |
| Statement of responsibility, etc | /Ayesha Kanwal |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Lahore : |
| Name of publisher, distributor, etc | Department of Chemistry, Div. S&T, University of Education, |
| Date of publication, distribution, etc | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 77 p. |
| Other physical details | xii |
| Accompanying material | CD |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Several substituted chalcones, aurones and isoxazolic aurones were synthesized. 2'-hydroxy acetophenone and various substituted benzaldehyde were used as precursor to synthesize chalcones. Synthesized chalcones on oxidative cyclization in presence of mercury (II) acetate in pyridine yielded aurones. Respective aurones were treated with hydroxylamine hydrochloride in ethanolic potassium hydroxide to form final<br/>isoxazolic aurones. Synthesized compounds were bioscreened for exhibiting antioxidant activity. Among all, some compounds were found to have potent anti-oxidant activity. Compound 5c was found to exhibit maximum radical scavenging and reduction potential. 7b showed lowest radical scavenging activity while 3c showed lowest reduction potential. Structure of compounds has been confirmed by IR and EIMS. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Characterization - Bioscreening - Isoxazolic - Chemistry |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Theses |
| Withdrawn status | Damaged status | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| UE-Central Library | UE-Central Library | 07.07.2022 | 547.2 Sy78 | TTH21 | 07.07.2022 | 07.07.2022 | Theses |
