TY  - BOOK
AU  - Martin,Yvonne Connolly
TI  - Quantitative drug design: a critical introduction 
SN  - 9781420070996 (hardcover : alk. paper)
U1  - 615.19 22
PY  - 2010///
CY  - Boca Raton
PB  - CRC Press/Taylor & Francis
KW  - Drugs
KW  - Structure-activity relationships
KW  - QSAR (Biochemistry)
KW  - Design
KW  - Drug Design
KW  - Biopharmaceutics
KW  - Models, Theoretical
KW  - Quantitative Structure-Activity Relationship
N1  - 1.	Overview of quantitative drug design 
2.	Noncovalent interactions in biological systems 
3.	Preparation of 3d structures of molecules for 3d qsar 
4.	Calculating physical properties of molecules 
5.	Biological data 
6.	Form of equations relating potency and physical properties 
7.	Statistical basis of regression and partial least-squares analysis 
8.	Strategy for the statistical evaluation of a data set of related molecules 
9.	Detailed examples of qsar calculations on erythromycin esters 
10.	Case studies 
11.	Methods to approach other structure-activity problems

ER  -